Barriers to Performing Soft Tissue Reconstruction Procedures among Orthopedic Surgeons in Low- and Middle-income Countries: Results of a Surgical Skills Training Course

Background:.Appropriate management of soft tissue injury associated with orthopedic trauma is challenging in low- and middle-income countries (LMICs) due to the lack of available reconstructive surgeons.The Surgical Management and Reconstructive Training (SMART) course teaches orthopedic surgeons reconstructive techniques aimed at improving soft ti

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Monoclonal antibody targeting of fibroblast growth factor receptor 1c ameliorates obesity and glucose intolerance via central mechanisms.

We have generated a novel monoclonal antibody targeting human FGFR1c (R1c mAb) that caused profound body weight and body fat loss in diet-induced obese mice due to decreased food intake (with energy expenditure unaltered), in turn improving glucose control.R1c mAb also caused weight loss in leptin-deficient ob/ob mice, leptin receptor-mutant db/db

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On The Metric Dimension of Some Operation Graphs

Let be a simple, finite, and connected graph.An ordered set of vertices of a Creamers nontrivial connected graph is and the -vector represent vertex that respect to , where and is the distance between vertex and for.The set called a resolving set for if different vertex of have different representations that respect to.The minimum of cardinality of

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